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Tumour cells shape their environment to protect them from the immune system

Tumour cells shape their environment to protect them from the immune system

Environment Connectz2 hours ago5 Views

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Tumour cells shape their environment to protect them from the immune system

RESEARCH BRIEFINGS
16 September 2026

A subset of pancreatic cancer cells express the genes SERPINE1 or SERPINB2, which form a molecular mesh around them. This sticky matrix helps to retain immunosuppressive cells and exclude the immune cells that kill cancer cells. Disrupting this process in mice improves immune control of pancreatic tumours and sensitizes them to immunotherapy.

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Health Connectz1 hour ago

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